Neuropsychological complications in patients with cerebral oncological disease: A review of the literature

Abstract

The incidence of primary CNS tumors is accentuated during childhood, however, in young adults and adults it is more common for metastatic tumors to appear, which appear as lesions originating in other regions of the body but with extensions that reach the central nervous system. The purpose of this work was to review the literature on neuropsychological complications in patients with oncological disease. Articles, books, manuals and specialized documents of scientific production were reviewed in the databases: Ebscohost, Scopus, Springer Protocols, Springer Journals, BioOne, Cambridge Journals Collection, Elsevier Science Direct, Wiley Online Library, Nature, Emerald, Google Bocks, Google Scholar, PubMed, Dialnet, SciELO, DOAJ, Latindex y REDIB, using descriptors in English, Portuguese or Spanish. Through the qualitative data analysis program ATLAS.ti, version 9, it was possible to classify by category family for neurocognitive deficit and oncological disease. In this sense, the subcategories were reviewed: cortical and subcortical region, based on primary and secondary tumors and neuropsychological complications. The relational networks obtained from this process allowed to codify, organize and identify cross-references of the concepts, as well as the realization of this bibliographic review. The development of cancer cells, their location and the size of the tumor mass, primary or secondary, define the impact and limitations of their deficits at the functional and neurocognitive level, which often put the autonomy and quality of life of patients at risk the patients.